Biotin & Vitamin D3 Information
What is Biotin?
Biotin is a B-complex vitamin, also known as B7 or Vitamin H. Biotin is necessary for the cell growth and the production of fatty acids in living organisms.
How it works?
Biotin converts fatty acids and glucose into fuel to produce energy. It helps to produce enzymes by metabolizing amino acids and carbohydrates.
What it treats?
- Aid in healthy sweat glands
- Nerve tissue and bone marrow
- Treats acne and eczema
- Strengthen hair and nails
- Aid in preventing hair loss
- Increase metabolism and speed up weight loss
- Improves blood glucose.
How is it administered?
Injection or as pills\ These uses have been tested in humans or animals. Safety and effectiveness have not always been proven. Some of these conditions are potentially serious and should be evaluated by a qualified healthcare provider. Biotin deficiency is rare in developed countries. The symptoms of biotin deficiency are similar, regardless of the underlying cause. Symptoms include conjunctivitis, developmental delay in infants and children, hair loss, low muscle tone, metabolic changes, skin lesions around the mouth and other body openings, seizures, and uncoordinated body movements. Biotin deficiency may generally be treated by biotin supplementation without adverse effects.
Inborn errors of metabolism, such as defects in any of the enzymes that bind to biotin, can cause functional biotin deficiency. Biotin-responsive basal ganglia disease has been reported. Biotin deficiency due to inborn errors of metabolism can generally be treated with very high doses of biotin without adverse effects.
Biotin has been routinely included in parenteral nutrition for over 25 years. Biotin deficiency associated with parenteral nutrition has not been reported since this practice was adopted.
Biotin has been used as a treatment for brittle fingernails. Additional studies are needed before a conclusion can be made. Treatment with biotin and the nutritional supplement chromium picolinate reduced cholesterol and blood lipids in patients with diabetes mellitus type 2 who were also taking standard blood sugar-lowering agents by mouth. Additional research on the effect of biotin alone is needed.
Biotin may play a role in maintenance of glucose tolerance. Treatment with biotin and the nutritional supplement chromium picolinate improved glycemic control in overweight and obese individuals with diabetes mellitus type 2 who were also taking standard blood sugar-lowering agents by mouth. Additional research on the effect of biotin alone is needed.
Biotin has been included in a therapeutic treatment plan for newborn infants with convulsions and epileptic syndromes. Additional research is required.
- Reports of allergy or anaphylaxis to biotin supplementation are rare.
Side Effects and Warnings
- Biotin is a water-soluble, B-complex vitamin that is required in the human diet. It is likely safe at levels typically found in food. Supplementation with pharmacological doses of biotin is considered safe and has been associated with minor (mild gastrointestinal upset) or no side effects. One case of hives has been reported. Biotin is considered safe in cosmetic formulations.
- Use cautiously in patients, including children, taking anticonvulsants (such as carbamazepine, phenytoin, phenobarbital, primidone (Mysoline®), or valproic acid), as anticonvulsant therapy may accelerate biotin breakdown and cause biotin deficiency.
Interactions with Drugs
- Biotin may lower blood sugar levels. Caution is advised when using medications that may also lower blood sugar. Patients taking insulin or drugs for diabetes by mouth should be monitored closely by a qualified healthcare professional, including a pharmacist. Medication adjustments may be necessary.
- Biotin may interfere with the way the body processes certain drugs using the liver’s cytochrome P450 enzyme system. As a result, the levels of these drugs may be increased in the blood and may cause increased effects or potentially serious adverse reactions. Patients using any medications should check the package insert and speak with a qualified healthcare professional, including a pharmacist, about possible interactions.
- Biotin may also interact with broad-spectrum antibiotics (such as sulfa drugs, sulfathalidine), anticonvulsants (such as carbamazepine, phenytoin, phenobarbital, primidone (Mysoline®), or valproic acid), isotretinoin (Roaccutane®), or lipid- or cholesterol-lowering agents.
Note: Smoking may lead accelerate biotin breakdown in women and
cause marginal biotin deficiency.
Interactions with Herbs and Supplements
- Biotin may lower blood sugar levels. Caution is advised when using herbs or supplements that may also lower blood sugar. Blood glucose levels may require monitoring, and doses may need adjustment.
- Biotin may interfere with the way the body processes certain herbs or supplements using the liver’s cytochrome P450 enzyme system. As a result, the levels of other herbs or supplements may become too high in the blood. It may also alter the effects that other herbs or supplements possibly have on the P450 system.
- Biotin may also interact with chromium picolinate, lipid- or cholesterollowering agents, lipoic acid, pantothenic acid (vitamin B5), or raw egg whites.
Why do we need Vitamin D?
- Facilitates normal immune system function
- Development of bones and teeth
- Decreases the chance of developing heart disease
- Regulates mood and wards off depression
- Has an appetite suppressing effect (weight loss)
What is causing a large portion of the population to be vitamin D deficient?
- Spending less time outdoors
- Use of sunscreen
- Vegetarian or vegan diets
***It is difficult to get enough vitamin D each day through sun exposure and food alone, therefore periodic supplementation with vitamin d injections is ideal.***
Vitamin D3 50,000IU 10ml vial
Vitamin D3 50,000IU 30ml vial